Your First PI Will Probably Leave Your Clinical Research Startup Site

I have seen time and time again, both personally, and in my work with clinical research sites all over the world, that a site's Principal Investigator is really what will determine a site's ultimate success or failure.  Typically, and especially with new sites, PI's will ultimately leave their first site either to start their own once they figure out the business aspects, join a competitor, or retire from clinical trials altogether.  Knowing this, research sites should constantly be recruiting new Investigators to join their organizations.   Never get too dependent on one PI!