Clinical trials can get quite complex and many research clinics have started noticing even more complicated protocols as the number of total research sites continues to increase every year. It is no wonder that many site directors and study coordinators may get intimidated when confronted with a particular assessment, or perhaps a piece of equipment that the Sponsor requires the site to have. Fortunately, everything and anything can be outsourced by the site to specialists who routinely conduct said assessments. As a general rule, I never tell a Sponsor that I cannot do something. If I am unsure of what they are even referring to, I still reply with "I will find out for you". Hope this helps!